Controlled Release of Ursodeoxycholic Acid from Pullulan Acetate Nanoparticles to Modulate Glutamate-Induced Excitotoxicity in PC-12 Cells
نویسندگان
چکیده
منابع مشابه
Ursodeoxycholic acid inhibits TNFα-induced IL-8 release from monocytes.
Monocytes are critical to the pathogenesis of inflammatory bowel disease (IBD) as they infiltrate the mucosa and release cytokines that drive the inflammatory response. Ursodeoxycholic acid (UDCA), a naturally occurring bile acid with anti-inflammatory actions, has been proposed as a potential new therapy for IBD. However, its effects on monocyte function are not yet known. Primary monocytes fr...
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Silymarin is having antioxidant and membrane stabilizing property and acts as a defensive material in different toxic forms of liver diseases like liver cirrhosis, alcoholic liver disease. Pullulan is a good water soluble neutral linear polysaccharide consisting of α-1,6 linked maltotriose residues. It is broadly used as a food additive and is considered to be safe for human use. In the present...
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ژورنال
عنوان ژورنال: Journal of Nanomaterials
سال: 2018
ISSN: 1687-4110,1687-4129
DOI: 10.1155/2018/7130450